Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T: Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo area.
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For example, human SET7/9 has just lately been reported to methylate Lys189 in the basic transcription issue TAF10, resulting in an elevated affinity for RNA polymerase II and transcriptional activation of certain TAF10-dependent genes 37 SET7/9 has additionally been reported to methylate p53, growing the steadiness of this quick lived tumor-suppressor protein 38 These observations counsel that we should not narrowly outline the SET-domain proteins as histone lysine methyltransferases but as a substitute call them protein lysine methyltransferases.
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